Sydney tech entrepreneur Paul Conyngham used ChatGPT to help sequence his dog Rosie's tumor DNA and design a personalized mRNA cancer vaccine, collaborating with UNSW RNA Institute director Páll Thordarson to create the world's first personalized cancer vaccine for dogs. The vaccine shrunk Rosie's mast cell tumors by 75% within a month of treatment, after traditional chemotherapy had failed. This represents a breakthrough application of AI-assisted personalized medicine extending from human healthcare into veterinary treatment.